Abnormal Composition of Very Low Density Lipoprotein in Experimental Nephrosis
نویسندگان
چکیده
منابع مشابه
Catabolism of very low density lipoproteins in experimental nephrosis.
The effects of experimental nephrosis in rats, produced by puromycin aminonucleoside, include an elevation of plasma levels of all lipoprotein density classes and the appearance of high density lipoprotein (HDL) rich in apoprotein (apo) A-I and deficient in apo A-IV and apo E. The hyperlipoproteinemia is associated with an increase in hepatic synthesis of lipoproteins. The possible role of decr...
متن کاملAbnormal composition of hypertriglyceridemic very low density lipoprotein determines abnormal cell metabolism.
The metabolism of very low density lipoprotein (VLDL) from normolipemic (NTG) subjects, hypertriglyceridemic (HTG) subjects, and hypertriglyceridemic subjects treated with bezafibrate (BZ) was studied in cultured human skin fibroblasts. The binding, cell association, and proteolytic degradation of 125I-labeled lipoproteins and the capacity to regulate cellular sterol synthesis was determined wi...
متن کاملLipoprotein metabolism in experimental nephrosis.
In experimental nephrosis, a decrease in plasma albumin resulting from proteinuria causes a decreased in the plasma oncotic pressure. The existence of an osmoreceptor, which responds to the low oncotic pressure and produces a factor(s) that signals the liver to increase the secretion of plasma proteins, is postulated. The hyperlipidemia characteristic of the nephrotic syndrome results primarily...
متن کاملVery-low density lipoprotein metabolism.
This manuscript was presented in part at the 31st Annual Meeting of the Council on Arteriosclerosis, American Society for the Study of Arteriosclerosis, American Heart Association. 1977. Circulation. 56(Suppl. III): 22. (Abstr.) Received for publication 2 December 1977 and in revised form 9 February 1978. and apoC) contained by negative staining, many disklike structures. The study demonstrated...
متن کاملVery Low Density Lipoprotein (VLDL)
Triglyceride (TG) or more accurately triacylglycerol is simply a compound of three acyl groups (fatty acids) attached to a glycerol molecule. They are easily measured in the laboratory and reported as serum TG level: it actually refers to all of the TG that are being trafficked within all of the lipoproteins that exist in a deciliter of plasma. A physiologic fasting TG concentration is on avera...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Japan Atherosclerosis Society
سال: 1990
ISSN: 0386-2682,2185-8284
DOI: 10.5551/jat1973.18.6_667